All Creatures Great and Small

New and emerging chlamydial infections of creatures great and small

Until recently, our knowledge of the host range and diversity of members of the Chlamydiaceae, obligate intracellular bacterial pathogens of humans and animals, was thought to be nearly complete. Aided by advances in molecular diagnostics, a new picture is emerging, however, that the host barriers may be looser than previously thought for many chlamydial species. While cross-host transmission o...

All Secrets Great and Small

Tools for analysing secure information flow are almost exclusively based on ideas going back to Denning’s work from the 70’s. This approach embodies an imperfect notion of security which turns a blind eye to information flows which are encoded in the termination behaviour of a program. In exchange for this weakness many more programs are deemed ”secure”, using conditions which are easy to check...

Of Creatures Great and Small: The Advantages of Farm Animal Models in Immunology Research

host-pathogen interactions that occur in outbred populations. A fundamental point in the development of new and improved intervention strategies is the understanding of host differences in the innate immune response, which primes the subsequent adaptive immune response. Although the innate immune system has been largely conserved during evolution, marked variations and diversity exist between d...

Incisions great and small.

Why Are We by All Creatures Waited on?

P ainter, engraver, designer of woodcuts, Lucas Cranach the Elder lived and worked during the last part of the Renaissance and embodied the integrative qualities valued by his age. In addition to accomplished artist, he was a successful entrepreneur, civic leader, and brilliant inventor. Among other innovations, he is credited with infl uencing the Danube school, a circle of painters along the ...